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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06d89f1d924c86abe577d5727a989f4fbac228b11e1658fec7bec502b50510d' 
  AND token = '2HTZ3mRtoObwtp8rPjkFZYXvjL8A7CliM6nyO9DFoXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}