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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4108f0d23437c41ff38193ad078d32f65c207b8424baef8bf9c844f4e7d885c2' 
  AND token = 'cdPEp3GLBNE4U65wJVPn4bvehPgMbXUdVL6RHm8CTAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}