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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b81406b326d82d232ee4513f2c05eb9b888e85e42941e1dac1ef58a488c12d4' 
  AND token = '+VS11jgYDMF+q/jbTPpe+3Xua8dfDFM0NWQF5Lw8fLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}