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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5e1f64487b12d0e5fac0ca14fe37fe038cc4ea82f509218379c68a3ca1bb81' 
  AND token = 'JpJrMytz92xhv2cOzlOHon+HA67vDlAbX2be26hKVhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}