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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bcea5d67c9e198d2e8beb9e5d7e8e3d5ee021162064272515573e4158727019' 
  AND token = 'Qz5gkoJD7nbuZ+5Fqw2kLXanxBJuKU9UXVKO3TQ9tvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}