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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2518b00e3c7ba33be918f5c40cb11f744cf43c054afff6f3f176b868fe483f14' 
  AND token = 'a1KmVlokl7rxUl3zDwB9W7nQQW5sLeacsn1r+cc0gBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}